Vaginal and oral microbes, host genotype and preterm birth
نویسندگان
چکیده
منابع مشابه
Vaginal bleeding during pregnancy and preterm birth.
This study investigated the relation between self-reported vaginal bleeding during pregnancy and preterm birth in a prospective cohort of 2,829 pregnant women enrolled from prenatal clinics between 1995 and 2000 in central North Carolina. The overall association between vaginal bleeding and preterm birth was modest (risk ratio (RR) = 1.3, 95% confidence interval (CI): 1.1, 1.6). Bleeding in the...
متن کاملWhat have we learned about vaginal infections and preterm birth?
Asymptomatic maternal genital tract infection during pregnancy, particularly bacterial vaginosis, has been consistently associated with preterm birth. In response to this evidence, the Maternal-Fetal Medicine Units Network (MFMU) designed and conducted 2 large randomized, placebo-controlled clinical trials of metronidazole treatment of asymptomatic pregnant women with bacterial vaginosis or tri...
متن کاملUreaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women
BACKGROUND Detection of Ureaplasma, Mycoplasma and Candida spp. in the vagina during pregnancy has previously been associated with preterm birth (PTB). However, the prevalence of these microorganisms and the associated obstetric risks (likely to be population-specific) have not been determined in Australian women; furthermore, in the case of Ureaplasma spp., very few studies have attempted char...
متن کاملThe interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk
BACKGROUND Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In specific patient cohorts, vaginal progesterone reduces this risk. Using 16S rRNA gene sequencing, we undertook a prospective study in women at risk of preterm birth (n = 161) to assess (1) the relationship between vaginal microbiota ...
متن کاملThe Prevalence of Vaginal Microorganisms in Pregnant Women with Preterm Labor and Preterm Birth
BACKGROUND To investigate the risk factors for vaginal infections and antimicrobial susceptibilities of vaginal microorganisms among women who experienced preterm birth (PTB), we compared the prevalence of vaginal microorganisms between women who experienced preterm labor (PTL) without preterm delivery and spontaneous PTB. METHODS Vaginal swab specimens from 126 pregnant women who experienced...
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ژورنال
عنوان ژورنال: Medical Hypotheses
سال: 2009
ISSN: 0306-9877
DOI: 10.1016/j.mehy.2009.06.017